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Mathematical Modelling of Nitric Oxide/Cyclic GMP/Cyclic AMP Signalling in Platelets

Platelet activation contributes to normal haemostasis but also to pathologic conditions like stroke and cardiac infarction. Signalling by cGMP and cAMP inhibit platelet activation and are therefore attractive targets for thrombosis prevention. However, extensive cross-talk between the cGMP and cAMP...

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Detalles Bibliográficos
Publicado en:Int J Mol Sci
Main Authors: Kleppe, Rune, Jonassen, Inge, Døskeland, Stein Ove, Selheim, Frode
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855834/
https://ncbi.nlm.nih.gov/pubmed/29462984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020612
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