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Mathematical Modelling of Nitric Oxide/Cyclic GMP/Cyclic AMP Signalling in Platelets

Platelet activation contributes to normal haemostasis but also to pathologic conditions like stroke and cardiac infarction. Signalling by cGMP and cAMP inhibit platelet activation and are therefore attractive targets for thrombosis prevention. However, extensive cross-talk between the cGMP and cAMP...

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Vydáno v:Int J Mol Sci
Hlavní autoři: Kleppe, Rune, Jonassen, Inge, Døskeland, Stein Ove, Selheim, Frode
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855834/
https://ncbi.nlm.nih.gov/pubmed/29462984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020612
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