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Mathematical Modelling of Nitric Oxide/Cyclic GMP/Cyclic AMP Signalling in Platelets

Platelet activation contributes to normal haemostasis but also to pathologic conditions like stroke and cardiac infarction. Signalling by cGMP and cAMP inhibit platelet activation and are therefore attractive targets for thrombosis prevention. However, extensive cross-talk between the cGMP and cAMP...

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Bibliografiske detaljer
Udgivet i:Int J Mol Sci
Main Authors: Kleppe, Rune, Jonassen, Inge, Døskeland, Stein Ove, Selheim, Frode
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855834/
https://ncbi.nlm.nih.gov/pubmed/29462984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020612
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