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Mathematical Modelling of Nitric Oxide/Cyclic GMP/Cyclic AMP Signalling in Platelets

Platelet activation contributes to normal haemostasis but also to pathologic conditions like stroke and cardiac infarction. Signalling by cGMP and cAMP inhibit platelet activation and are therefore attractive targets for thrombosis prevention. However, extensive cross-talk between the cGMP and cAMP...

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Pubblicato in:Int J Mol Sci
Autori principali: Kleppe, Rune, Jonassen, Inge, Døskeland, Stein Ove, Selheim, Frode
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5855834/
https://ncbi.nlm.nih.gov/pubmed/29462984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19020612
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