CD40 stimulation accelerates deletion of tumor-specific CD8(+) T cells in the absence of tumor-antigen vaccination

Previous work has established a role for CD40-mediated signals in eliciting helper-dependent CD8(+) T cell responses. Here we investigated the effects of in vivo CD40 stimulation on the survival and function of tumor-specific CD8(+) T cells in a mouse melanoma model system. We found that agonistic a...

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Detalles Bibliográficos
Autores principales: Kedl, Ross M., Jordan, Michael, Potter, Terence, Kappler, John, Marrack, Philippa, Dow, Steven
Formato: Artigo
Lenguaje:Inglês
Publicado: The National Academy of Sciences 2001
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC58556/
https://ncbi.nlm.nih.gov/pubmed/11526222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.191371898
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