VTA mTOR Signaling Regulates Dopamine Dynamics, Cocaine-Induced Synaptic Alterations, and Reward

Mechanistic target of rapamycin (mTOR) regulates long-term synaptic plasticity, learning, and memory by controlling dendritic protein synthesis. The mTOR inhibitor rapamycin has been shown to attenuate the behavioral effects of drugs of abuse, including cocaine. Using viral vectors to selectively de...

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Vydáno v:Neuropsychopharmacology
Hlavní autoři: Liu, Xiaojie, Li, Yan, Yu, Laikang, Vickstrom, Casey R, Liu, Qing-song
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2018
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854804/
https://ncbi.nlm.nih.gov/pubmed/29039413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2017.247
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