The Epac-Phospholipase Cε Pathway Regulates Endocannabinoid Signaling and Cocaine-Induced Disinhibition of Ventral Tegmental Area Dopamine Neurons

Exchange protein directly activated by cAMP (Epac) is a direct effector for the ubiquitous second messenger cAMP. Epac activates the phospholipase Cε (PLCε) pathway. PLCβ has been linked to the synthesis of the endocannabinoid 2-arachidonoylglycerol (2-AG). Here, we report that Epac facilitates endo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Tong, Jiaqing, Liu, Xiaojie, Vickstrom, Casey, Li, Yan, Yu, Laikang, Lu, Youming, Smrcka, Alan V., Liu, Qing-Song
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2017
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354337/
https://ncbi.nlm.nih.gov/pubmed/28209735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2810-16.2017
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados