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Subcellular localisation modulates ubiquitylation and degradation of Ascl1

The proneural transcription factor Ascl1 is a master regulator of neurogenesis, coordinating proliferation and differentiation in the central nervous system. While its expression is well characterised, post-translational regulation is much less well understood. Here we demonstrate that a population...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Gillotin, Sébastien, Davies, John D., Philpott, Anna
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5854709/
https://ncbi.nlm.nih.gov/pubmed/29545540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-23056-4
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