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Exploiting rhodium-catalysed ynamide hydroacylation as a platform for divergent heterocycle synthesis

The first examples of ynamide hydroacylation are described. Using rhodium catalysis, linear β-enaminone products are generated in high yield and excellent regioselectivity from the combination of aldehydes and ynamides. The enaminone products are subsequently used as a platform to construct a divers...

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Vydáno v:Chem Sci
Hlavní autoři: Straker, Robert N., Majhail, Manjeet K., Willis, Michael C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2017
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853270/
https://ncbi.nlm.nih.gov/pubmed/29568442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7sc03795c
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