Prenatal dexamethasone and postnatal high-fat diet have a synergistic effect of elevating blood pressure through a distinct programming mechanism of systemic and adipose renin–angiotensin systems

BACKGROUND: Hypertension may result from high-fat (HF) diet induced-obesity and overexposure to glucocorticoids in utero. Recent studies demonstrated the potent contribution of adipose tissue’s renin-angiotensin system (RAS) to systemic RAS, which plays a key role in regulating blood pressure (BP)....

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Detalhes bibliográficos
Publicado no:Lipids Health Dis
Main Authors: Yu, Hong-Ren, Tain, You-Lin, Tiao, Mao-Meng, Chen, Chih-Cheng, Sheen, Jiunn-Ming, Lin, I-Chun, Li, Shih-Wen, Tsai, Ching-Chou, Lin, Yu-Ju, Hsieh, Kai-Sheng, Huang, Li-Tung
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853160/
https://ncbi.nlm.nih.gov/pubmed/29540174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12944-018-0701-0
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