Maternal Melatonin Therapy Rescues Prenatal Dexamethasone and Postnatal High-Fat Diet Induced Programmed Hypertension in Male Rat Offspring

Prenatal dexamethasone (DEX) exposure and high-fat (HF) intake are linked to hypertension. We examined whether maternal melatonin therapy prevents programmed hypertension synergistically induced by prenatal DEX plus postnatal HF in adult offspring. We also examined whether DEX and melatonin causes r...

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Pubblicato in:Front Physiol
Autori principali: Tain, You-Lin, Sheen, Jiunn-Ming, Yu, Hong-Ren, Chen, Chih-Cheng, Tiao, Mao-Meng, Hsu, Chien-Ning, Lin, Yu-Ju, Kuo, Kuang-Che, Huang, Li-Tung
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2015
Soggetti:
Physiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675845/
https://ncbi.nlm.nih.gov/pubmed/26696906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00377
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