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Maternal Melatonin Therapy Rescues Prenatal Dexamethasone and Postnatal High-Fat Diet Induced Programmed Hypertension in Male Rat Offspring

Prenatal dexamethasone (DEX) exposure and high-fat (HF) intake are linked to hypertension. We examined whether maternal melatonin therapy prevents programmed hypertension synergistically induced by prenatal DEX plus postnatal HF in adult offspring. We also examined whether DEX and melatonin causes r...

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Publié dans:Front Physiol
Auteurs principaux: Tain, You-Lin, Sheen, Jiunn-Ming, Yu, Hong-Ren, Chen, Chih-Cheng, Tiao, Mao-Meng, Hsu, Chien-Ning, Lin, Yu-Ju, Kuo, Kuang-Che, Huang, Li-Tung
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675845/
https://ncbi.nlm.nih.gov/pubmed/26696906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00377
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