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Maternal Melatonin Therapy Rescues Prenatal Dexamethasone and Postnatal High-Fat Diet Induced Programmed Hypertension in Male Rat Offspring

Prenatal dexamethasone (DEX) exposure and high-fat (HF) intake are linked to hypertension. We examined whether maternal melatonin therapy prevents programmed hypertension synergistically induced by prenatal DEX plus postnatal HF in adult offspring. We also examined whether DEX and melatonin causes r...

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Vydáno v:Front Physiol
Hlavní autoři: Tain, You-Lin, Sheen, Jiunn-Ming, Yu, Hong-Ren, Chen, Chih-Cheng, Tiao, Mao-Meng, Hsu, Chien-Ning, Lin, Yu-Ju, Kuo, Kuang-Che, Huang, Li-Tung
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4675845/
https://ncbi.nlm.nih.gov/pubmed/26696906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2015.00377
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