Early Postweaning Treatment with Dimethyl Fumarate Prevents Prenatal Dexamethasone- and Postnatal High-Fat Diet-Induced Programmed Hypertension in Male Rat Offspring

Prenatal dexamethasone (DEX) exposure, postnatal high-fat (HF) intake, and oxidative stress are closely related to the development of hypertension. Nuclear factor erythroid-derived 2-related factor 2 (Nrf2) regulates oxidative stress. Dimethyl fumarate (DMF) reportedly activates Nrf2 and protects ag...

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Vydáno v:Oxid Med Cell Longev
Hlavní autoři: Lin, Yu-Ju, Lin, I-Chun, Yu, Hong-Ren, Sheen, Jiunn-Ming, Huang, Li-Tung, Tain, You-Lin
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2018
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5832129/
https://ncbi.nlm.nih.gov/pubmed/29636848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/5343462
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