Hypogalactosylation of immunoglobulin G in rheumatoid arthritis: relationship to HLA-DRB1 shared epitope, anticitrullinated protein antibodies, rheumatoid factor, and correlation with inflammatory activity

BACKGROUND: Galactosylation of immunoglobulin G (IgG) is reduced in rheumatoid arthritis (RA) and assumed to correlate with inflammation and altered humoral immunity. IgG hypogalactosylation also increases with age. To investigate dependencies in more detail, we compared IgG hypogalactosylation betw...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Schwedler, Christian, Häupl, Thomas, Kalus, Ulrich, Blanchard, Véronique, Burmester, Gerd-Rüdiger, Poddubnyy, Denis, Hoppe, Berthold
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5853146/
https://ncbi.nlm.nih.gov/pubmed/29540200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-018-1540-0
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