Identification of anticitrullinated protein antibody reactivities in a subset of anti-CCP-negative rheumatoid arthritis: association with cigarette smoking and HLA-DRB1 ‘shared epitope’ alleles

INTRODUCTION: A hallmark of rheumatoid arthritis (RA) is the development of autoantibodies targeting proteins that contain citrulline. Anticitrullinated protein antibodies (ACPAs) are currently detected by the commercial cyclic citrullinated peptide (CCP) assay, which uses a mix of cyclised citrulli...

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Bibliografske podrobnosti
izdano v:Ann Rheum Dis
Main Authors: Wagner, Catriona A, Sokolove, Jeremy, Lahey, Lauren J, Bengtsson, Camilla, Saevarsdottir, Saedis, Alfredsson, Lars, Delanoy, Michelle, Lindstrom, Tamsin M, Walker, Roger P, Bromberg, Reuven, Chandra, Piyanka E, Binder, Steven R, Klareskog, Lars, Robinson, William H
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2015
Teme:
Basic and Translational Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4345988/
https://ncbi.nlm.nih.gov/pubmed/24297382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2013-203915
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