Enhanced Operant Extinction and Prefrontal Excitability in a Mouse Model of Angelman Syndrome

Angelman syndrome (AS), a neurodevelopmental disorder associated with intellectual disability, is caused by loss of maternal allele expression of UBE3A in neurons. Mouse models of AS faithfully recapitulate disease phenotypes across multiple domains, including behavior. Yet in AS, there has been onl...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Sidorov, Michael S., Judson, Matthew C., Kim, Hyojin, Rougie, Marie, Ferrer, Alejandra I., Nikolova, Viktoriya D., Riddick, Natallia V., Moy, Sheryl S., Philpot, Benjamin D.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852653/
https://ncbi.nlm.nih.gov/pubmed/29431654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2828-17.2018
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