Enhanced Operant Extinction and Prefrontal Excitability in a Mouse Model of Angelman Syndrome

Angelman syndrome (AS), a neurodevelopmental disorder associated with intellectual disability, is caused by loss of maternal allele expression of UBE3A in neurons. Mouse models of AS faithfully recapitulate disease phenotypes across multiple domains, including behavior. Yet in AS, there has been onl...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Sidorov, Michael S., Judson, Matthew C., Kim, Hyojin, Rougie, Marie, Ferrer, Alejandra I., Nikolova, Viktoriya D., Riddick, Natallia V., Moy, Sheryl S., Philpot, Benjamin D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2018
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852653/
https://ncbi.nlm.nih.gov/pubmed/29431654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2828-17.2018
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