Optimizing EphA2-CAR T Cells for the Adoptive Immunotherapy of Glioma

Glioblastoma is the most aggressive primary brain tumor in humans and is virtually incurable with conventional therapies. Chimeric antigen receptor (CAR) T cell therapy targeting the glioblastoma antigen EphA2 is an attractive approach to improve outcomes because EphA2 is expressed highly in gliobla...

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Bibliografiske detaljer
Udgivet i:Mol Ther Methods Clin Dev
Main Authors: Yi, Zhongzhen, Prinzing, Brooke L., Cao, Felicia, Gottschalk, Stephen, Krenciute, Giedre
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852415/
https://ncbi.nlm.nih.gov/pubmed/29552579
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2018.01.009
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