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Identification of a small‐molecule ligand of β‐arrestin1 as an inhibitor of stromal fibroblast cell migration accelerated by cancer cells

Stromal fibroblasts, which occupy a major portion of the tumor microenvironment, play an important role in cancer metastasis. Thus, targeting of these fibroblasts activated by cancer cells (carcinoma‐associated fibroblasts; CAFs) might aid in the improved treatment of cancer metastasis. NIH3T3 fibro...

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Опубликовано в: :Cancer Med
Главные авторы: Suvarna, Kruthi, Honda, Kaori, Kondoh, Yasumitsu, Osada, Hiroyuki, Watanabe, Nobumoto
Формат: Artigo
Язык:Inglês
Опубликовано: John Wiley and Sons Inc. 2018
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852355/
https://ncbi.nlm.nih.gov/pubmed/29380537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.1339
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