The Esophageal Organoid System Reveals Functional Interplay Between Notch and Cytokines in Reactive Epithelial Changes

BACKGROUND & AIMS: Aberrations in the esophageal proliferation-differentiation gradient are histologic hallmarks in eosinophilic esophagitis (EoE) and gastroesophageal reflux disease. A reliable protocol to grow 3-dimensional (3D) esophageal organoids is needed to study esophageal epithelial hom...

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Detalhes bibliográficos
Publicado no:Cell Mol Gastroenterol Hepatol
Main Authors: Kasagi, Yuta, Chandramouleeswaran, Prasanna M., Whelan, Kelly A., Tanaka, Koji, Giroux, Veronique, Sharma, Medha, Wang, Joshua, Benitez, Alain J., DeMarshall, Maureen, Tobias, John W., Hamilton, Kathryn E., Falk, Gary W., Spergel, Jonathan M., Klein-Szanto, Andres J., Rustgi, Anil K., Muir, Amanda B., Nakagawa, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852293/
https://ncbi.nlm.nih.gov/pubmed/29552622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcmgh.2017.12.013
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