Loss of the adaptor protein ShcA in endothelial cells protects against monocyte macrophage adhesion, LDL-oxydation, and atherosclerotic lesion formation

ShcA is an adaptor protein that binds to the cytoplasmic tail of receptor tyrosine kinases and of the Low Density Lipoprotein-related receptor 1 (LRP1), a trans-membrane receptor that protects against atherosclerosis. Here, we examined the role of endothelial ShcA in atherosclerotic lesion formation...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Abou-Jaoude, Antoine, Badiqué, Lise, Mlih, Mohamed, Awan, Sara, Guo, Sunning, Lemle, Alexandre, Abboud, Clauda, Foppolo, Sophie, Host, Lionel, Terrand, Jérôme, Justiniano, Hélène, Herz, Joachim, Matz, Rachel L., Boucher, Philippe
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852050/
https://ncbi.nlm.nih.gov/pubmed/29540796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22819-3
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi