Isoform-specific knockdown and expression of adaptor protein ShcA using small interfering RNA.

Many eukaryotic genes are expressed as multiple isoforms through the differential utilization of transcription/translation initiation sites or alternative splicing. The conventional approach for studying individual isoforms in a clean background (i.e. without the influence of other isoforms) has bee...

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Bibliographic Details
Main Authors: Kisielow, Malgorzata, Kleiner, Sandra, Nagasawa, Michiaki, Faisal, Amir, Nagamine, Yoshikuni
Format: Artigo
Language:Inglês
Published: 2002
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1222444/
https://ncbi.nlm.nih.gov/pubmed/11903040
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