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Membrane-association of EMR2/ADGRE2-NTF is regulated by site-specific N-glycosylation

The evolutionarily conserved adhesion G protein-coupled receptors (aGPCRs) play critical roles in biological processes as diverse as brain development, cell polarity and innate immune functions. A defining feature of aGPCRs is the GPCR autoproteolysis inducing (GAIN) domain capable of self-catalytic...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huang, Yi-Shu, Chiang, Nien-Yi, Chang, Gin-Wen, Lin, Hsi-Hsien
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5852045/
https://ncbi.nlm.nih.gov/pubmed/29540735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22849-x
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