Dynamics of Escherichia coli type I-E CRISPR spacers over 42 000 years

CRISPR-Cas are nucleic acid-based prokaryotic immune systems. CRISPR arrays accumulate spacers from foreign DNA and provide resistance to mobile genetic elements containing identical or similar sequences. Thus, the set of spacers present in a given bacterium can be regarded as a record of encounters...

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Bibliographic Details
Published in:Mol Ecol
Main Authors: Savitskaya, Ekaterina, Lopatina, Anna, Medvedeva, Sofia, Kapustin, Mikhail, Shmakov, Sergey, Tikhonov, Alexey, Artamonova, Irena I., Logacheva, Maria, Severinov, Konstantin
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851898/
https://ncbi.nlm.nih.gov/pubmed/27997045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mec.13961
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