טוען...
Biomolecular study of human thymidylate synthase conformer-selective inhibitors: New chemotherapeutic approach
Thymidylate synthase (TS) is a well-validated target for the therapy of adult cancers. Propane-1,3-diphosphonic acid (PDPA) has significant inhibitory properties against human thymidylate synthase (hTS) relative to mouse TS which is not predicted to adopt an inactive conformer. The current research...
שמור ב:
| הוצא לאור ב: | PLoS One |
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| Main Authors: | , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Public Library of Science
2018
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5851609/ https://ncbi.nlm.nih.gov/pubmed/29538414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193810 |
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