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Human DNA repair genes possess potential G-quadruplex sequences in their promoters and 5`-untranslated regions

The cellular response to oxidative stress includes transcriptional changes, particularly for genes involved in DNA repair. Recently, our laboratory demonstrated that oxidation of 2`-deoxyguanosine (G) to 8-oxo-7,8-dihydro-2`-deoxyguanosine (OG) in G-rich potential G-quadruplex sequences (PQSs) in ge...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Fleming, Aaron M., Zhu, Judy, Ding, Yun, Visser, Joshua A., Zhu, Julia, Burrows, Cynthia J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5851598/
https://ncbi.nlm.nih.gov/pubmed/29320161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.7b01172
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