Probenecid Improves Cardiac Function in Patients With Heart Failure With Reduced Ejection Fraction In Vivo and Cardiomyocyte Calcium Sensitivity In Vitro

BACKGROUND: Transient receptor potential vanilloid 2 is a calcium channel activated by probenecid. Probenecid is a Food and Drug Administration–approved uricosuric drug that has recently been shown to induce positive lusitropic and inotropic effects in animal models through cardiomyocyte transient r...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Am Heart Assoc
Autors principals: Robbins, Nathan, Gilbert, Mark, Kumar, Mohit, McNamara, James W., Daly, Patrick, Koch, Sheryl E., Conway, Ginger, Effat, Mohamed, Woo, Jessica G., Sadayappan, Sakthivel, Rubinstein, Jack
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5850150/
https://ncbi.nlm.nih.gov/pubmed/29331959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.117.007148
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars