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Dual effect of PEG-PE micelle over the oligomerization and fibrillation of human islet amyloid polypeptide
The oligomerization and fibrillation of human islet amyloid polypeptide (hIAPP) play a central role in the pathogenesis of type 2 diabetes. Strategies for remodelling the formation of hIAPP oligomers and fibrils have promising application potential in type 2 diabetes therapy. Herein, we demonstrated...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5849606/ https://ncbi.nlm.nih.gov/pubmed/29535385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-22820-w |
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