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HDAC3 is a master regulator of mTEC development

The thymus provides a unique microenvironment enabling development and selection of T lymphocytes. Medullary thymic epithelial cells (mTECs) play a pivotal role in this process by facilitating negative selection of self-reactive thymocytes and the generation of Foxp3(+) regulatory T cells. Although...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Cell Rep
Egile Nagusiak: Goldfarb, Yael, Kadouri, Noam, Levi, Ben, Sela, Asaf, Herzig, Yonatan, Cohen, Ronald N, Hollenberg, Anthony, Abramson, Jakub
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849426/
https://ncbi.nlm.nih.gov/pubmed/27068467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.03.048
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