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Gene editing and gene-based therapeutics for cardiomyopathies

With an increasing understanding of genetic defects leading to cardiomyopathy, focus is shifting to methods for correcting these underlying genetic defects. One approach involves treating mutant RNA through antisense oligonucleotides, and the first drug has now received regulatory approval to treat...

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Bibliographic Details
Published in:Heart Fail Clin
Main Authors: Ohiri, Joyce C, McNally, Elizabeth M
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849064/
https://ncbi.nlm.nih.gov/pubmed/29525646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hfc.2017.12.006
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