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Population-Based Variation in Cardiomyopathy Genes

BACKGROUND: Hypertrophic cardiomyopathy and dilated cardiomyopathy arise from mutations in genes encoding sarcomere proteins including MYH7, MYBPC3, and TTN. Genetic diagnosis of cardiomyopathy relies on complete sequencing of the gene coding regions, and most pathogenic variation is rare. The 1000...

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Detalhes bibliográficos
Main Authors: Golbus, Jessica R., Puckelwartz, Megan J., Fahrenbach, John P., Dellefave-Castillo, Lisa M., Wolfgeher, Don, McNally, Elizabeth M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3495587/
https://ncbi.nlm.nih.gov/pubmed/22763267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCGENETICS.112.962928
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