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Gene editing and gene-based therapeutics for cardiomyopathies

With an increasing understanding of genetic defects leading to cardiomyopathy, focus is shifting to methods for correcting these underlying genetic defects. One approach involves treating mutant RNA through antisense oligonucleotides, and the first drug has now received regulatory approval to treat...

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Detalles Bibliográficos
Publicado en:Heart Fail Clin
Main Authors: Ohiri, Joyce C, McNally, Elizabeth M
Formato: Artigo
Idioma:Inglês
Publicado: 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849064/
https://ncbi.nlm.nih.gov/pubmed/29525646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.hfc.2017.12.006
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