Epithelial cell adhesion molecule overexpression regulates epithelial-mesenchymal transition, stemness and metastasis of nasopharyngeal carcinoma cells via the PTEN/AKT/mTOR pathway

Epithelial cell adhesion molecule (EpCAM) is known to be highly expressed in a variety of epithelial carcinomas, and it is involved in cell adhesion and proliferation. However, its expression profile and biological function in nasopharyngeal carcinoma (NPC) remains unclear. In this study, higher exp...

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Udgivet i:Cell Death Dis
Main Authors: Wang, Meng-He, Sun, Rui, Zhou, Xiao-Min, Zhang, Mei-Yin, Lu, Jia-Bin, Yang, Yang, Zeng, Li-Si, Yang, Xian-Zi, Shi, Lu, Xiao, Ruo-Wen, Wang, Hui-Yun, Mai, Shi-Juan
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849035/
https://ncbi.nlm.nih.gov/pubmed/29305578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0013-8
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