Epithelial cell adhesion molecule overexpression regulates epithelial-mesenchymal transition, stemness and metastasis of nasopharyngeal carcinoma cells via the PTEN/AKT/mTOR pathway

Epithelial cell adhesion molecule (EpCAM) is known to be highly expressed in a variety of epithelial carcinomas, and it is involved in cell adhesion and proliferation. However, its expression profile and biological function in nasopharyngeal carcinoma (NPC) remains unclear. In this study, higher exp...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Wang, Meng-He, Sun, Rui, Zhou, Xiao-Min, Zhang, Mei-Yin, Lu, Jia-Bin, Yang, Yang, Zeng, Li-Si, Yang, Xian-Zi, Shi, Lu, Xiao, Ruo-Wen, Wang, Hui-Yun, Mai, Shi-Juan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849035/
https://ncbi.nlm.nih.gov/pubmed/29305578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0013-8
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