Epithelial cell adhesion molecule overexpression regulates epithelial-mesenchymal transition, stemness and metastasis of nasopharyngeal carcinoma cells via the PTEN/AKT/mTOR pathway

Epithelial cell adhesion molecule (EpCAM) is known to be highly expressed in a variety of epithelial carcinomas, and it is involved in cell adhesion and proliferation. However, its expression profile and biological function in nasopharyngeal carcinoma (NPC) remains unclear. In this study, higher exp...

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Dettagli Bibliografici
Pubblicato in:Cell Death Dis
Autori principali: Wang, Meng-He, Sun, Rui, Zhou, Xiao-Min, Zhang, Mei-Yin, Lu, Jia-Bin, Yang, Yang, Zeng, Li-Si, Yang, Xian-Zi, Shi, Lu, Xiao, Ruo-Wen, Wang, Hui-Yun, Mai, Shi-Juan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5849035/
https://ncbi.nlm.nih.gov/pubmed/29305578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-017-0013-8
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