ZFX acts as a transcriptional activator in multiple types of human tumors by binding downstream from transcription start sites at the majority of CpG island promoters

High expression of the transcription factor ZFX is correlated with proliferation, tumorigenesis, and patient survival in multiple types of human cancers. However, the mechanism by which ZFX influences transcriptional regulation has not been determined. We performed ChIP-seq in four cancer cell lines...

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Detalhes bibliográficos
Publicado no:Genome Res
Main Authors: Rhie, Suhn Kyong, Yao, Lijun, Luo, Zhifei, Witt, Heather, Schreiner, Shannon, Guo, Yu, Perez, Andrew A., Farnham, Peggy J.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2018
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848610/
https://ncbi.nlm.nih.gov/pubmed/29429977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.228809.117
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