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ZFX acts as a transcriptional activator in multiple types of human tumors by binding downstream from transcription start sites at the majority of CpG island promoters

High expression of the transcription factor ZFX is correlated with proliferation, tumorigenesis, and patient survival in multiple types of human cancers. However, the mechanism by which ZFX influences transcriptional regulation has not been determined. We performed ChIP-seq in four cancer cell lines...

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Detalles Bibliográficos
Publicado en:Genome Res
Main Authors: Rhie, Suhn Kyong, Yao, Lijun, Luo, Zhifei, Witt, Heather, Schreiner, Shannon, Guo, Yu, Perez, Andrew A., Farnham, Peggy J.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5848610/
https://ncbi.nlm.nih.gov/pubmed/29429977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.228809.117
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