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Defining drug and target protein distributions after stent-based drug release: durable versus deployable coatings

BACKGROUND: Innovations in drug eluting stent designs make it increasingly important to develop models for differentiating performance through spatial definition of drug, receptor binding and cell state. METHODS: Two designs of sirolimus analog eluting stents were implanted into porcine coronary art...

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Bibliografiske detaljer
Udgivet i:J Control Release
Main Authors: Tzafriri, Abraham R., Garcia-Polite, Fernando, Li, Xiaojian, Keating, John, Balaguer, Josep-Maria, Zani, Brett, Bailey, Lynn, Markham, Peter, Kiorpes, Timothy C., Carlyle, Wenda, Edelman, Elazer R.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847480/
https://ncbi.nlm.nih.gov/pubmed/29421608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.02.007
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