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Stent elution rate determines drug deposition and receptor-mediated effects
Drug eluting stent designs abound and yet the dependence of efficacy on drug dose and elution duration remains unclear. We examined these issues within a mathematical framework of arterial drug distribution and receptor binding following stent elution. Model predictions that tissue content linearly...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3616625/ https://ncbi.nlm.nih.gov/pubmed/22642931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2012.05.039 |
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