Impact of multi-gene mutational profiling on clinical trial outcomes in metastatic breast cancer

PURPOSE: Next-generation sequencing (NGS) has identified recurrent genomic alterations in metastatic breast cancer (MBC); however, the clinical utility of incorporating routine sequencing to guide treatment decisions in this setting is unclear. We examine the frequency of genomic alterations in MBC...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Principais autores: Pezo, Rossanna C., Chen, Tom W., Berman, Hal K., Mulligan, Anna M., Razak, Albiruni A., Siu, Lillian L., Cescon, David W., Amir, Eitan, Elser, Christine, Warr, David G., Sridhar, Srikala S., Yu, Celeste, Wang, Lisa, Stockley, Tracy L., Kamel-Reid, Suzanne, Bedard, Philippe L.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Clinical Trial
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847065/
https://ncbi.nlm.nih.gov/pubmed/29177603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-017-4580-2
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