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Early phase clinical trials to identify optimal dosing and safety

The purpose of early stage clinical trials is to determine the recommended dose and toxicity profile of an investigational agent or multi‐drug combination. Molecularly targeted agents (MTAs) and immunotherapies have distinct toxicities from chemotherapies that are often not dose dependent and can le...

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Detalhes bibliográficos
Publicado no:Mol Oncol
Main Authors: Cook, Natalie, Hansen, Aaron R., Siu, Lillian L., Abdul Razak, Albiruni R.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329110/
https://ncbi.nlm.nih.gov/pubmed/25160636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.07.025
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