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Early phase clinical trials to identify optimal dosing and safety

The purpose of early stage clinical trials is to determine the recommended dose and toxicity profile of an investigational agent or multi‐drug combination. Molecularly targeted agents (MTAs) and immunotherapies have distinct toxicities from chemotherapies that are often not dose dependent and can le...

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Podrobná bibliografie
Vydáno v:Mol Oncol
Hlavní autoři: Cook, Natalie, Hansen, Aaron R., Siu, Lillian L., Abdul Razak, Albiruni R.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4329110/
https://ncbi.nlm.nih.gov/pubmed/25160636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.07.025
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