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The Utility of Hedgehog Signaling Pathway Inhibition for Cancer
The Hedgehog (Hh) signaling pathway has been implicated in tumor initiation and metastasis across different malignancies. Major mechanisms by which the Hh pathway is aberrantly activated can be attributed to mutations of members of Hh pathway or excessive/inappropriate expression of Hh pathway ligan...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
AlphaMed Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3425527/ https://ncbi.nlm.nih.gov/pubmed/22851551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2011-0450 |
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