Synergistic enhancing-memory effect of donepezil and S 47445, an AMPA positive allosteric modulator, in middle-aged and aged mice

Positive allosteric modulators of AMPA receptors (AMPA-PAMs) are described to facilitate cognitive processes in different memory-based models. Among them, S 47445 is a novel potent and selective AMPA-PAM. In order to assess its efficacy after repeated administration, S 47445 effect was evaluated in...

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Bibliographic Details
Published in:Psychopharmacology (Berl)
Main Authors: Bretin, S., Krazem, A., Henkous, N., Froger-Colleaux, C., Mocaer, E., Louis, C., Perdaems, N., Marighetto, A., Beracochea, D.
Format: Artigo
Language:Inglês
Published: Springer Berlin Heidelberg 2017
Subjects:
Original Investigation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5847048/
https://ncbi.nlm.nih.gov/pubmed/29167913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-017-4792-5
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