Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers

Genetic defects in the synaptic scaffolding protein gene, SHANK2, are linked to a variety of neuropsychiatric disorders, including autism spectrum disorders, schizophrenia, intellectual disability, and bipolar disorder, but the molecular mechanisms underlying the pleotropic effects of SHANK2 mutatio...

詳細記述

保存先:
書誌詳細
出版年:JCI Insight
主要な著者: Pappas, Andrea L., Bey, Alexandra L., Wang, Xiaoming, Rossi, Mark, Kim, Yong Ho, Yan, Haidun, Porkka, Fiona, Duffney, Lara J., Phillips, Samantha M., Cao, Xinyu, Ding, Jin-dong, Rodriguiz, Ramona M., Yin, Henry H., Weinberg, Richard J., Ji, Ru-Rong, Wetsel, William C., Jiang, Yong-hui
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 2017
主題:
Research Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846902/
https://ncbi.nlm.nih.gov/pubmed/29046483
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92052
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