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Deficiency of Shank2 causes mania-like behavior that responds to mood stabilizers
Genetic defects in the synaptic scaffolding protein gene, SHANK2, are linked to a variety of neuropsychiatric disorders, including autism spectrum disorders, schizophrenia, intellectual disability, and bipolar disorder, but the molecular mechanisms underlying the pleotropic effects of SHANK2 mutatio...
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| Publicado no: | JCI Insight |
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| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846902/ https://ncbi.nlm.nih.gov/pubmed/29046483 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.92052 |
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