High-resolution detection of chromosomal rearrangements in leukemias through mate pair whole genome sequencing

The detection of recurrent somatic chromosomal rearrangements is standard of care for most leukemia types. Even though karyotype analysis—a low-resolution genome-wide chromosome analysis—is still the gold standard, it often needs to be complemented with other methods to increase resolution. To evalu...

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Vydáno v:PLoS One
Hlavní autoři: Tran, Anh Nhi, Taylan, Fulya, Zachariadis, Vasilios, Ivanov Öfverholm, Ingegerd, Lindstrand, Anna, Vezzi, Francesco, Lötstedt, Britta, Nordenskjöld, Magnus, Nordgren, Ann, Nilsson, Daniel, Barbany, Gisela
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846771/
https://ncbi.nlm.nih.gov/pubmed/29529047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193928
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