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High-resolution detection of chromosomal rearrangements in leukemias through mate pair whole genome sequencing

The detection of recurrent somatic chromosomal rearrangements is standard of care for most leukemia types. Even though karyotype analysis—a low-resolution genome-wide chromosome analysis—is still the gold standard, it often needs to be complemented with other methods to increase resolution. To evalu...

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Bibliografiska uppgifter
I publikationen:PLoS One
Huvudupphovsmän: Tran, Anh Nhi, Taylan, Fulya, Zachariadis, Vasilios, Ivanov Öfverholm, Ingegerd, Lindstrand, Anna, Vezzi, Francesco, Lötstedt, Britta, Nordenskjöld, Magnus, Nordgren, Ann, Nilsson, Daniel, Barbany, Gisela
Materialtyp: Artigo
Språk:Inglês
Publicerad: Public Library of Science 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846771/
https://ncbi.nlm.nih.gov/pubmed/29529047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193928
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