High-resolution detection of chromosomal rearrangements in leukemias through mate pair whole genome sequencing

The detection of recurrent somatic chromosomal rearrangements is standard of care for most leukemia types. Even though karyotype analysis—a low-resolution genome-wide chromosome analysis—is still the gold standard, it often needs to be complemented with other methods to increase resolution. To evalu...

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Publicat a:PLoS One
Autors principals: Tran, Anh Nhi, Taylan, Fulya, Zachariadis, Vasilios, Ivanov Öfverholm, Ingegerd, Lindstrand, Anna, Vezzi, Francesco, Lötstedt, Britta, Nordenskjöld, Magnus, Nordgren, Ann, Nilsson, Daniel, Barbany, Gisela
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2018
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846771/
https://ncbi.nlm.nih.gov/pubmed/29529047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0193928
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