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In vivo evaluation of IGF1R/IR PET ligand [(18)F]BMS-754807 in rodents
In vivo evaluation of [(18)F]BMS-754807 binding in mice and rats using microPET and biodistribution methods is described herein. The radioligand shows consistent binding characteristics, in vivo, in both species. Early time frames of the microPET images and time activity curves of brain indicate poo...
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| Publicat a: | Bioorg Med Chem Lett |
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| Autors principals: | , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2017
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846678/ https://ncbi.nlm.nih.gov/pubmed/28094184 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.12.086 |
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