In vivo evaluation of IGF1R/IR PET ligand [(18)F]BMS-754807 in rodents

In vivo evaluation of [(18)F]BMS-754807 binding in mice and rats using microPET and biodistribution methods is described herein. The radioligand shows consistent binding characteristics, in vivo, in both species. Early time frames of the microPET images and time activity curves of brain indicate poo...

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Publicat a:Bioorg Med Chem Lett
Autors principals: Prabhakaran, Jaya, Dewey, Stephen L., McClure, Richard, Simpson, Norman R., Tantawy, Mohammed N., Mann, J. John, Pham, Wellington, Kumar, J.S. Dileep
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846678/
https://ncbi.nlm.nih.gov/pubmed/28094184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.12.086
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