In vivo evaluation of IGF1R/IR PET ligand [(18)F]BMS-754807 in rodents

In vivo evaluation of [(18)F]BMS-754807 binding in mice and rats using microPET and biodistribution methods is described herein. The radioligand shows consistent binding characteristics, in vivo, in both species. Early time frames of the microPET images and time activity curves of brain indicate poo...

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Bibliografske podrobnosti
izdano v:Bioorg Med Chem Lett
Main Authors: Prabhakaran, Jaya, Dewey, Stephen L., McClure, Richard, Simpson, Norman R., Tantawy, Mohammed N., Mann, J. John, Pham, Wellington, Kumar, J.S. Dileep
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846678/
https://ncbi.nlm.nih.gov/pubmed/28094184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2016.12.086
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