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Targeting potassium channels to treat cerebellar ataxia
OBJECTIVE: Purkinje neuron dysfunction is associated with cerebellar ataxia. In a mouse model of spinocerebellar ataxia type 1 (SCA1), reduced potassium channel function contributes to altered membrane excitability resulting in impaired Purkinje neuron spiking. We sought to determine the relationshi...
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| Publicado no: | Ann Clin Transl Neurol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5846455/ https://ncbi.nlm.nih.gov/pubmed/29560375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.527 |
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