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Modular domain swapping among the bacterial cytotoxic necrotizing factor (CNF) family for efficient cargo delivery into mammalian cells

Modular AB-type bacterial protein toxins target mammalian host cells with high specificity and deliver their toxic cargo into the cytosol. Hence, these toxins are being explored as agents for targeted cytosolic delivery in biomedical and research applications. The cytotoxic necrotizing factor (CNF)...

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Foilsithe in:J Biol Chem
Main Authors: Haywood, Elizabeth E., Ho, Mengfei, Wilson, Brenda A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Biochemistry and Molecular Biology 2018
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5846154/
https://ncbi.nlm.nih.gov/pubmed/29371399
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA117.001381
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