The Cytotoxic Necrotizing Factor of Yersinia pseudotuberculosis (CNF(Y)) Enhances Inflammation and Yop Delivery during Infection by Activation of Rho GTPases

Some isolates of Yersinia pseudotuberculosis produce the cytotoxic necrotizing factor (CNF(Y)), but the functional consequences of this toxin for host-pathogen interactions during the infection are unknown. In the present study we show that CNF(Y) has a strong influence on virulence. We demonstrate...

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Autores principales: Schweer, Janina, Kulkarni, Devesha, Kochut, Annika, Pezoldt, Joern, Pisano, Fabio, Pils, Marina C., Genth, Harald, Huehn, Jochen, Dersch, Petra
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820761/
https://ncbi.nlm.nih.gov/pubmed/24244167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003746
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