The Cytotoxic Necrotizing Factor of Yersinia pseudotuberculosis (CNF(Y)) Enhances Inflammation and Yop Delivery during Infection by Activation of Rho GTPases

Some isolates of Yersinia pseudotuberculosis produce the cytotoxic necrotizing factor (CNF(Y)), but the functional consequences of this toxin for host-pathogen interactions during the infection are unknown. In the present study we show that CNF(Y) has a strong influence on virulence. We demonstrate...

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Hlavní autoři: Schweer, Janina, Kulkarni, Devesha, Kochut, Annika, Pezoldt, Joern, Pisano, Fabio, Pils, Marina C., Genth, Harald, Huehn, Jochen, Dersch, Petra
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2013
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3820761/
https://ncbi.nlm.nih.gov/pubmed/24244167
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003746
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